Multiple sclerosis ms is a chronic, autoimmune, inflammatory, demyelinating disease of the central nervous system. National institutes of health bethesda, maryland 20892 nih publication no. The earliest record of ms dates back to 1837, when carswell and cruveilhier separately described the histological lesions of ms in the central nervous system cns 1,2. Please use one of the following formats to cite this article in your essay, paper or report. Natalizumab therapy for highly active pediatric multiple sclerosis. Esclerosis multiple em es una enfermedad desmielinizante del sistema nervioso central. Multiple sclerosis ms is a disorder characterized by a demyelinating, autoimmune and inflammatory process of the nervous system. Sep 17, 2016 multiple sclerosis ms is a chronic, autoimmune, inflammatory, demyelinating disease of the central nervous system. Multiple sclerosis ms is the most important immunemediated demyelinated disease of the humanbeings. Consensus definitions proposed for pediatric multiple sclerosis and related disorders. The exact etiology of ms is still not known, although autoimmune, genetic, and environmental factors play important roles in its development, making it a.
Ms in childhood, like in adults, is believed to involve a complex interaction between environmental triggers such as infections, genetic predisposition, and an abnormal autoimmune response. Elizabeth mcdonald, mbbs, fafrm, racp, directora medica, ms australia. Kornek b, aboulenein f, rostasy k, milos ri, steiner i, penzien j, et al. Expression of metabotropic glutamate receptors in multiple sclerosis brain. Feb 27, 2019 please use one of the following formats to cite this article in your essay, paper or report. Esclerosis multiple y cuidados del paciente esclerosis. Esclerosis multiple informacion en espanol national. It is the leading cause of disability in this group. Pdf on dec 1, 2011, juan farfan and others published esclerosis multiple. The clinical course is usually characterized by severe. P a c ie n te c o n d ia g n o s tic o d e s in d r o m e c l in ic o a is l a d o a fe c c io n n e u ro lo g ic a m o n o o p o lis in to m a tic a c o n u n a d u ra c io n m a y o r a 2 4 h o ra s, q u e e s s u g e s tiv a d e e n fe rm e d a d. International pediatric multiple sclerosis study group criteria for pediatric multiple sclerosis and immune mediated central nervous system demyelinating disorders.
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